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Although the therapies resulted in similar change on the 17-item hamilton depression rating scale, remission rates were significantly higher among those treated with bupropion xl 46 versus venlafaxine xr 33 .

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the auc and cmax of hydroxybupropion metabolite were decreased by 50 and 31 , respectively.

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the rate of life-threatening or lethal outcomes for suicidal overdoses of venlafaxine is lower than for the tcas, maois, and bupropion but higher than almost all of the ssris, and equal to citalopram.

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